Martin Andreas Santini
Chief Executive OfficerMartin is the Chief Executive Officer of Clinical Microbiomics. Prior to joining Clinical Microbiomics in 2016, Martin worked with R&D and corporate strategy in the Danish biotech company Novozymes as part of the R&D Leadership Team. Martin is well-versed in strategy and business development through his tenure as a management consultant in Bain & Company, mainly within the pharma and biotech area. Extensive experience within the private equity sector positions him well to understand market developments and opportunities. Martin holds a MSc in Human Biology from University of Copenhagen and a PhD in Health and Medical Sciences from the University of Copenhagen and Harvard Medical School.
Henrik Bjørn Nielsen
Chief Scientific OfficerBjørn, PhD, is Chief Scientific Officer (CSO) at Clinical Microbiomics. Bjørn is part of the leadership team together with the CEO and CBO. He is responsible for directing the science team and our scientific innovation. Moreover, Bjørn oversees all client projects. Bjørn has an outstanding background as both group-leader at the Technical University of Denmark and has been a frontrunner in the field of microbiome research for more than a decade. He has published more than 20 high-visibility publications within the microbiome field, covering biomedical discoveries and a series of key analysis concepts for microbiome data. Bjørn has extensive expertise in analyzing, integrating and managing diverse types of data. With his experience and innovative mindset, Bjørn has played a key role in establishing Clinical Microbiomics as the leading CRO for advanced microbiome analysis.
Klaus Gamst Hansen
Director of Sales & Business DevelopmentKlaus joined Clinical Microbiomics when the company was founded in 2015. He has a background within commercialization and start-up analytical work in Danish consultancy company TTO (part of Plougmann Vingtoft). Klaus' responsibilities include sales, marketing and communication activities combined with work in business development, competitive intelligence, representing the company at conferences and building partnerships and collaborations across the EU and US. Klaus holds a MSc in Medical Biology and Communication Studies from Roskilde University.
Director of BioinformaticsAron has a key role in developing our bioinformatics pipelines and workflows. He is involved in client project management and performing statistical analysis. Aron has specialized expertise in development and application of cutting-edge genomics and computational methods for cancer diagnosis, personalized treatment, and target discovery of immuntherapy. This includes methods to infer homologous recombination, DNA repari deficiency, tumor copy number profiles, and the origin of metastatic cancers of unknown primary, as well as methods to both predict and experimentally validate tumor neoantigens. Aron holds a MSc in Biology from Massachusetts Institute of Technology and a PhD in Systems Biology from the Technical University of Denmark. He became part of our team in August 2017.
Director of Scientific Operations & Quality AssuranceNikolaj is involved throughout the whole timeline of our client's projects. He has a key role in our quality assurance and is responsible for and has also designed our Q&A system from which we received the ISO 17025 certification in the beginning of 2018. Nikolaj has a string ecological background with extensive knowledge in molecular analysis of microorganisms allowing him to gain deep insight into the microbial world. His specialized area of expertise include finding linkage between nutrition, diseases and the gut microflora. Nikolaj holds PhD from the University of Copenhagen. This research focused in microbial ecology from the Center for Macroecology, Evolution and Climate. Nikolaj has been part of the team since 2016.
Sales & Business Development ManagerMarianne recently finished her PhD in Clinical Medicine Research at Imperial College London abd also holds a master in Molecular Biotechnology from Lund Technical University in Sweden. During her PhD Marianne studied the gut-lung axis and the effect of gut microbial metabolites on the airway epithelium and microbiota in asthmatics, and metabolic profiling to identify potential biomarkers that could aid the diagnoses of asthma. Marianne's solid knowledge in microbiomics makes her a strong addition to our sales team which she joined in November 2019.
Jacob Bak Holm
Director of Scientific OperationsJacob is involved in our studies from the very beginning to end. He is in charge of our internal project development such as our Skin Microbiome Platform including both skin-optimized laboratory protocols and data analysis. His area of expertise is the microbiome in relation to host, metabolism, immune response and pathogens. Jacob also has experience with a broad variety of animal and human studies focusing on how diet, pathogens, diseases, prebiotics and probiotics modulate the gut microbiota and what potential functional consequences this can have for the host. Jacob holds a MSc in Molecular Biomedicine from the University of Copenhagen and a PhD in Laboratory of Genomics and Molucular Biomedicine from the Institute of Biology at University of Copenhagen. He became part of our team in November 2016.
Director of Scientific OperationsTimo's expertise is the bridging between our laboratory processes and bioinformatic analysis. He is leading our microbiome projects from beginning to end. Timo has acquired extensive experience in planning and performing large-scale studies exploring the global human microbiome and human genetics; managing both the technical challenges of the wet lab and the analysis of high-dimensional sequencing data. Timo holds a MSc in Molecular Biology from the University of Frankfurt and a PhD from the Novo Nordisk Foundation Center for Basic Metabolic Research. During his PhD, Timo was particularly interested in exploring host-microbiome interactions and the influence of metabolic diseases, lifestyle, and other environmental factors of the human gastrointestinal microbiome. Moreover, he studied the role of the oral microbiome in the pathogenesis of metabolic disorders and liver diseases. He joined our team in January 2019.
Director of Scientific OperationsThorsten is an experienced microbiome scientist and his competences bridge lab and bioinformatics which will be instrumental for your absolute microbiome abundance profiling offerings and much more. He holds a bachelor and a master's degree in molecular biotechnology from the University og Heidelberg in Germany. During his PhD he studied the regulation of vesicular trafficking pathways, endocytosis and autophagy, at EMBL. He continued his career at CBMR at University of Copenhagen after receiving a Marie Curie Individual Fellowship to investigate age-associated changes in the way our immune system reacts to gut microbes. At CBMT he further studied the role of gut microbes in cirrhosis progression as part of the European liver disease consortia. Thorstens research has contributed to well-cited scientific publications in the field of redox biology, vesicular trafficking and gut microbiome research. He joined our team in November 2019.
Albert Pallejà Caro
Bioinformatics SpecialistAlbert is one of our bioinformatics specialists carrying out mainly shotgun metagenomics projects, from QC processing of the sequencing reads and data crunching to statistical analysis and visualization of results. Albert has led various shotgun metagenomics studies characterizing the effects of interventions targeting directly or indirectly the human, pig or mice gut microbiota. He is specialized in the effects of antibiotic treatment of the gut microbiota and in the resistome (understood as collection of antibiotic resistance genes) characterization. Besides this, Albert has broad expertise within several disciplines of bioinformatics including comparative genomics, human protein networks related to human disease and omics integration. Albert holds a PhD in Bacterial Genomics and a MSc in Chemistry and Biochemistry, both from the University Rovira i Virgili in Tarragona, Catalunya. He became part of our team in May 2017.
Andrea Marion Marquard
Bioinformatic SpecialistAndrea is specialized in NGS-based technologies in relation to immunotherapy and cancer research. She holds a PhD in Cancer Genomics from the center for Biological Sequence Analysis at the Technical University of Denmark. Moreover, a MSc in Molecular Biomedicine from the University of Copenhagen. During her PhD studies Andrea developed analyses tools for high-throughput screening of antigen responses in patients based on DNA-barcode tagged libraries which is today used to identify tumor neoantigens and antigens in autoimmune diseases. Moreover, a tool to describe a T cell’s recognition fingerprint that can help predict cross-recognition of T cells intended for clinical development. Andrea joined our team in August 2019.
Bioinformatics SpecialistHelle is one of our bioinformatics specialists specialized in integrative systems biology approached in type 2 diabetes and related disorders. Helle holds a PhD in integrative systems biology in type 2 diabetes from the Center for Biological Sequence Analysis at the Technical University of Denmark (DTU). Moreover, a master’s degree in Systems Biology also from the DTU.
Machine Learning SpecialistKonrad is our machine learning specialist. He works to improve our pipelines and data analysis with a special focus on improving our abilities to infer statistical associations between host phenotypes and microbial communities. Konrad holds a MSc in Biotechnology from Jagiellonian University of Krakow and a PhD in Bioinformatics from Groningen Bioinformatics Centre at University of Groningen. He joined our team in October 2018.
Bioinformatics Specialist (On leave)Oksana works as science lead for many of our shotgun metagenomics projects where she is responsible for performing bioinformatics analyses and visualization of the results. At the moment she is on maternity leave. Oksana holds a PhD in Microbial Comparative Genomics from the Technical University of Denmark (DTU). She is specialized in the global surveillance of infectious diseases and antimicrobial resistance. Moreover, she holds a master’s degree of Science in Biotechnology also from DTU. She joined our team in April 2018.
Laboratory ManagerPia is a key player in ensuring our high quality of DNA extractions and sample preparations for 16S MiSeq sequencing and metagenomic shotgun sequencing. She has broad experience within laboratory work in different scientific areas. Among her experiences, Pia has been responsible for setting up a molecular laboratory at Makerere University in Uganda and has developed fluorescent proteins at Joint Institute fir Laboratory Astrophysics in Colorado. Also, Pia was involved in was involved in some of the early microbiome projects during the Metagenomics of the Human Intestinal Tract consortium and therefor have extensive knowledge in the area of microbiome extractions. Pia has been part of our team since January 2018.
Project ManagerNynne is working in our laboratory with our pipeline for DNA extraction from very beginning to end. She takes part in our innovation projects such as optimizing extraction protocols for various types of skin samples. Nynne holds a BSc and a MSc in Molecular Biomedicine from University of Copenhagen. During her research she has been working with bacterial interactions in multispecies biofilms and applied modelling approaches to study the interspecies interactions in biofilms relevant for industrial food facilities. Nynne Joined our team in September 2017.
Bioinformatics AssistantGustav works on our internal bioinformatic projects. This could be examining different ways of detecting bacteriophages in the human microbiome. Gustav holds a bachelor’s degree in Biotechnology from the Technical University of Denmark. Currently, he studies a MSc in Bioinformatics and Systems Biology also from DTU which is very focused on statistics, machine learning and modelling. He joined our team in 2018 to write his bachelors thesis.
Klara Elise Nygaard
Laboratory AssistantKlara is assisting in our laboratory where she does laboratory work such as sample handling, DNA extractions, library preparation and sequencing. Also, she assists in bioinformatical analyses of the microbiome and optimization of the efficiency and innovation of the methods used in the laboratory. Klara holds a bachelor's degree in Molecular Biomedicine from the University of Copenhagen and joined our team in February 2019.
Alberte Wollesen Breum
Laboratory AssistantAlberte is assisting in our laboratory while studying a bachelor’s degree in Molecular Biomedicine from the University of Copenhagen. She does laboratory work such as sample handling, DNA extractions, library preparation and sequencing. Also, she assists in bioinformatical analyses of the microbiome and optimization of the efficiency and innovation of the methods used in the laboratory. Alberte joined our team in October 2019.
Anders Østergaard Petersen
PhD StudentAnders is doing his PhD together with us and the Health Technology Institute at the Technical University of Denmark. He have a background in chemistry and pharmaceutical design also from DTU and has always been very keen on programming and bioinformatics. Anders’ PhD focuses on correlating functional annotation of gut bacteria to clinical measures and creating actionable and legible insights into the microbiome. Anders’ main emphases has been on complex correlations between microbiome, bile acids and health. He is trying to gain insights into the capacity of the human microbiome to drive human serum concentrations of bile acids, as well as gaining insights into the correlations between the immune system and microbiome. Anders joined our team in September 2016 to write his master thesis concerning bacterial metabolism of C-6 hydroxylated bile acids, their production in the gut and their effect on human health.
PhD StudentPernille is one of our young talented PhD students from the Technical University of Denmark (DTU). She is working with us as a bioinformatics specialist developing our SNV-level resolution pipeline for tracking therapeutic microbes in intervention studies and our metagenomic species database for the infant gut microbiome. In her PhD research, she studies the development of the gut microbiome of small children, how it interacts with the immune system and how this may lead to childhood obesity or allergies. Pernille is dedicated to developing ultra-high-ressolution methodologies for analyzing the gut microbiome. Pernille holds a Mac in Bioinformatics Engineering and Systems Biology also from DTU. She joined our team as a master thesis student in August 2016.
PhD StudentDennis is one of our young talented PhD students working with us while during his PhD in collaboration with the Technical University of Denmark (DTU). He is part of the prestigious EU Horizon 2020 Best Treat Programme aiming at developing new diagnostics and treatments for non-alcoholic fatty lever diseases (NAFLD). The purpose of Dennis' research is to identify microbiome keystone-species for the systems diversity, stability of human health from longitudinal microbiome data. For this, Dennis will develop a framework for estimating microbial persistence and colonization probabilities. Also, he works on identifying metabolic disease related strains from meta-omic data analysis. Dennis holds a MSc in Bioinformatics and is doing his PhD research at DTU Biosustain department. In his master theses, Dennis estimated the impact of a 6-day course of antibiotic treatment on bacterial replication rates in a metagenomics time-series experiment.